In a few words...
The GReD is a Research Center at Clermont-Ferrand, Auvergne Rhône Alpes region of France ...
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CALL for a NEW RESEARCH GROUP LEADER,
The GReD Institute opens a position of Independent Group Leader in human mobility related fields.
As part of the CAP20-25 initiative , the successful candidate will benefit from a 400 k€ start-up package and the GReD Institute will provide office, appropriate lab space and access to in-house facilities.
The final deadline for applications is noon, January 31st 2021.
For more details and apply , it's here

Labellisation LIGUE de l’équipe MOP@ET
Félicitation à l’équipe MOP@ET qui vient d’obtenir la labélisation de La Ligue Nationale Contre le Cancer pour une période de 5 ans. Ce label prestigieux est une reconnaissance du travail mené depuis plusieurs années par cette équipe sur le cancer de la surrénale.

When LXR plays firefighters….
Chronic inflammation is a precursor mechanism supporting cancer development. Regarding the prostate, although hormone deprivation therapy significantly slows down cancer development, it triggers deep alterations in the tumor microenvironment. In its last studi, published in Genome Biology ( Bousset et al.) the NuReP team shows that the absence of nuclear receptors LXR leads to reprogramming of the tumor microenvironment, in particular the immune landscape.

Replicate to repress
Heterochromatin, which states for highly condensed genomics regions, is mainly constituted of transcriptionally repressed repeated elements. In its last study, published in Genome Biology (Bourguet et al., 2020), the SILENT team shows that DNA polymerase epsilon, which is involved in DNA replication, plays a crucial role in maintaining both the structure and the function of heterochromatin.

Post-doc available : “Identification of natural extracts targeting LXR nuclear receptors activity involved in skin wound healing”
A 2 years post-doc position, shared between the GRed and GREENTECH company, is available in the "Nuclear receptors and prostate diseases" from august 2021
For more details and to apply, it’s here.


Three new young CNRS/INSERM researchers at the GReD in 2020...what else ?!
2020 Competitive Examinations for CNRS and INSERM Researchers has been a great vintage for the GReD as all its three candidates have been appointed.
We are thus happy and proud to acknowledge three new Chargés de recherche : Julia EYCHENNE (section Inter-Disciplinaire 52 CNRS), Antoine MOLARO (CSS1 INSERM) et Heïdi SERRA (Section 23 CNRS).

Post-doc available to valorize a treatment Strategy by sevoflurane of the Acute Respiratory Distress Syndrome COVID-19
A 30 months post-doc position is available in the "Translational approach to epithelial injury and repair" team to work on the ASTRA project: "Biomedical and industrial valorization of a Treatment Strategy by sevoflurane of the Acute Respiratory Distress Syndrome COVID-19, based on the RAGE signaling pathway",
For more details and to apply, it’s here.
Contact: Matthieu Jabaudon email: matthieu.jabaudon-gandet@uca.fr

Les Doctorantes du GReD s’illustrent lors des JED 2020.
Amy HESKETH (Equipe “SILENT”), Marianne YOTH (Equipe “Instabilités génétiques et contrôle par le génome hôte”) et Manon BOULET (“Régulation épigénétique et hématopoïèse”) ont toutes trois été primées lors des Journées de l’école Doctorale 2020. Elles ont respectivement reçu le prix des meilleures communications orales de GREENTECH et de l’ecole Doctorale.
Ces prix, attribués par un jury de chercheurs du public et du privé, leur permettront d'exercer leur talent d’orateur dans un congrès International. Félicitations à elles.

A new research group has joined the GReD
Awarded in 2020 by the FRM "Young Investigator " programm, Antoine Molaro has joined the GRed this summer to develop its thematic on Evolutionary Epigenomics and Genetic Conflicts.
He his supported in this journey by Marine Fraisse and both they can count on their trusty companions "Steeve" and "Brian" .
To know more, it's here