Thematic 2: Reproduction and development in health and disease
Cell differentiation is a leitmotiv in embryonic development and reproduction to produce various cell types such as germinal, epithelial or muscular cells. The environment, mainly neighboring cells or/and the physiological context, plays an essential role in orchestrating proper cell differentiation programs. Impairment of this program leads to developmental defects or to pathologies such as infertility, cancer or dystrophy. Four research groups of the GReD laboratory are studying cell differentiation at the levels of cell determination, maturation, diversification and morphogenesis of different cell types using genetic, molecular and imaging tools in vertebrate and invertebrate animal models.
- Team 06: Molecular mechanisms of cell lineage differentiation in the early mouse embryo - Leader(s): Claire CHAZAUD
- Team 07: Mechanisms of mammalian post-testicular infertility - Leader(s): Joel DREVET
- Team 08: Diversification of muscle and heart cells in normal and pathological conditions - Leader(s): Krzysztof JAGLA
- Team 09: Epithelial Growth and Morphogenesis - Leader(s): Vincent MIROUSE
- Team 10: Translational approach to epithelial injury and repair - Leader(s): Vincent SAPIN
- Team 16: Role of Environmental Cues in Axis Morphogenesis - Leader(s): Charlene GUILLOT