Team 11: Nuclear receptors and prostate diseases

“Lipids, nuclear receptors and male disorders”

The primary goal of our group is to understand and discriminate the respective roles of the lipid related nuclear receptors (namely LXR, FXR and SHP) in the control of the endocrine activity in males. For that purpose we use complementary as well as parallel approaches to answer these questions: new or already available mouse models and various cell models. The research project is focused on two complementary topics: 1) Control of the lipid homeostasis in the reproductive functions by studying the physiologic role of LXRs in the testis and the impact of bile acids on male reproductive functions. 2) Impact of lipids on prostate physiology and pathology (benign prostate hyperplasia and prostate cancer).

Research

 Projet de l'équipe de L. Morel

Research thematics

People

Last Name First Name Position Contact
Silvere BARON profile picture BARON Silvere Principal Investigator
Erwan BOUCHAREB profile picture BOUCHAREB Erwan Ph.D Student
Sarah DALLEL profile picture DALLEL Sarah Ph.D Student
Christelle DAMON-SOUBEYRAND profile picture DAMON-SOUBEYRAND Christelle Assistant Engineer
Sabrina DEHAY profile picture DEHAY Sabrina Research Engineer
Cyrille DE JOUSSINEAU profile picture DE JOUSSINEAU Cyrille Associate Professor
Hamzaoui EYA profile picture EYA Hamzaoui Intern
Ayhan KOCER profile picture KOCER Ayhan Associate Professor
Jean-Marc LOBACCARO profile picture LOBACCARO Jean-Marc Professor
Elodie MARTIN profile picture MARTIN Elodie Ph.D Student
Laurent MOREL profile picture MOREL Laurent Professor
Jean-Paul SARU profile picture SARU Jean-Paul Research Technician
Amalia TROUSSON profile picture TROUSSON Amalia Associate Professor
Marine VIALAT profile picture VIALAT Marine Ph.D Student

Publications