Team: Environment, Metabolism, spermatogenesis, pathophysiology and inheritance






we would like to have a friendly thought for our colleague and friend Bernard Jégou who passed away. We will miss you. Thank you my friend. Kenavo!

Congratulations to Laura for her 4th year funding obtained from the FRM.

We have an available post-doc position in our lab open.

Our team has been laureate of 3 years funding from  Plan Cancer Contrat for the 3R call.

 Welcome to Lucie who is starting her post-doc, and will start working on the impacts of ashes on health.


 Welcome to Alexis who is starting his master-2 research in our team, and who will work on C. Elegans and Dafachronic.

Rencontre patients/chercheur Inserm


Thrusday 27th of February 2020 3:00 pm; Dr DavidVOLLE (Inserm U 1103, CNRS UMR6293–Université Clermont Auvergne) will present his work on "Bile acid signaling in male reproduction at the Inserm Unit 1185, PARIS

13th November 2019, Our team will present his work  on Environment and Healthto patient associatons. (CRBC, Clermont, Ferrand).

Congratulation to Hélène for her article In The Journal of Steroid Biochemistry and Molecular Biology. Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis

Congratulation to Manon and Laura for their article review in Cell Mol Life Sci.. Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system.

Congratulation to Laura who was awarded at the Doctoral School Days 2019. She received the prize for the best poster.

Welcome to Guerric who is starting his master-2 research in our team, and who will work on C. Elegans and Dafachronic.

Congratulations to Mélusine who won the Junior Prize of the Society of French-speaking Andrology for her M2 work in our team.

Féliciations à Marine pour son papierdansScientific Reports "Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways."


Félicitations à Manon pour sa revue "Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases." dans Int J Mol Sci.

Congratulation to Claude who obtain funding from the Ligue contre le cancer for his work on FXRalpha in the etiology of testicular germ cell cancer.

Féliciations à Lauriane pour son papier dans Stem Cell Reports "Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders."

Congratulation to Mélusine who succeed in her MASTER-2R and will start PhD with us in October 2018.

Wellcome to Melusine, Master-2R student, working on molecular mechanisms of spermatogenesis.

We will start studying spermatogenesis using C ELegans thanks to our financial support from the French government IDEX-ISITE initiative 16-IDEX-0001 (CAP 20-25)/ Emergence program.

Félicitations à Manon et Claude pour l'obtention d'une bourse de thèse de la FRM.

Félicitations à Laura pour l'obtention de son contrat doctoral, nous serons heureux de la retrouver en Septembre prochaine avec nous!

Félicitations à Manon pour son prix de thèse de la Ligue contre le cancer

Féliciations à Emmanuelle pour son papier dans Stem Cell Reports "The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate"

Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders.

Research thematics


Last Name First Name Position Contact
Claude BEAUDOIN profile picture BEAUDOIN Claude Professor
Francoise CAIRA profile picture CAIRA Francoise Associate Professor
Christelle DAMON-SOUBEYRAND profile picture DAMON-SOUBEYRAND Christelle Assistant Engineer
Sabrina DEHAY profile picture DEHAY Sabrina Research Engineer
Angelique DE HAZE profile picture DE HAZE Angelique Assistant Engineer
Manon GARCIA profile picture GARCIA Manon Ph.D Student
Helene HOLOTA profile picture HOLOTA Helene Engineer
Mickael JOUVE profile picture JOUVE Mickael Intern
Emmanuelle MARTINOT profile picture MARTINOT Emmanuelle Post-doctoral Fellow
Melusine MONROSE profile picture MONROSE Melusine Ph.D Student
Elise PLASSE profile picture PLASSE Elise Intern
Jean-Paul SARU profile picture SARU Jean-Paul Research Technician
Lucie SAUZEAT profile picture SAUZEAT Lucie Post-doctoral Fellow
Laura THIROUARD profile picture THIROUARD Laura Ph.D Student
David VOLLE profile picture VOLLE David Principal Investigator