Team 11: Nuclear receptors and prostate diseases

“Lipids, nuclear receptors and male disorders”

The primary goal of our group is to understand and discriminate the respective roles of the lipid related nuclear receptors (namely LXR, FXR and SHP) in the control of the endocrine activity in males. For that purpose we use complementary as well as parallel approaches to answer these questions: new or already available mouse models and various cell models. The research project is focused on two complementary topics: 1) Control of the lipid homeostasis in the reproductive functions by studying the physiologic role of LXRs in the testis and the impact of bile acids on male reproductive functions. 2) Impact of lipids on prostate physiology and pathology (benign prostate hyperplasia and prostate cancer).

Research

 Projet de l'équipe de L. Morel

Research thematics

People

Last Name First Name Position Contact
Silvere BARON profile picture BARON Silvere Principal Investigator
Laura BOUSSET profile picture BOUSSET Laura Ph.D Student
Julio Arduino BUNAY-NOBOA profile picture BUNAY-NOBOA Julio Arduino Post-doctoral Fellow
Olivier CELHAY profile picture CELHAY Olivier Ph.D Student
Cyrille DE JOUSSINEAU profile picture DE JOUSSINEAU Cyrille Associate Professor
Allan FOUACHE profile picture FOUACHE Allan Ph.D Student
Jean-Marc LOBACCARO profile picture LOBACCARO Jean-Marc Professor
Laurent MOREL profile picture MOREL Laurent Professor
Amandine RAMBUR profile picture RAMBUR Amandine Ph.D Student
Jean-Paul SARU profile picture SARU Jean-Paul Technical Assistant
Amalia TROUSSON profile picture TROUSSON Amalia Associate Professor

Publications