Team 11: Nuclear receptors and prostate diseases

“Lipids, nuclear receptors and male disorders”

The primary goal of our group is to understand and discriminate the respective roles of the lipid related nuclear receptors (namely LXR, FXR and SHP) in the control of the endocrine activity in males. For that purpose we use complementary as well as parallel approaches to answer these questions: new or already available mouse models and various cell models. The research project is focused on two complementary topics: 1) Control of the lipid homeostasis in the reproductive functions by studying the physiologic role of LXRs in the testis and the impact of bile acids on male reproductive functions. 2) Impact of lipids on prostate physiology and pathology (benign prostate hyperplasia and prostate cancer).

Research

 Projet de l'équipe de L. Morel

Research thematics

People

Last Name First Name Position Contact
Silvere BARON profile picture BARON Silvere Principal Investigator
Laura BOUSSET profile picture BOUSSET Laura Ph.D Student
Hadjer BRIHOUM profile picture BRIHOUM Hadjer Intern
Julio Arduino BUNAY-NOBOA profile picture BUNAY-NOBOA Julio Arduino Post-doctoral Fellow
Sarah DALLEL profile picture DALLEL Sarah Intern
Cyrille DE JOUSSINEAU profile picture DE JOUSSINEAU Cyrille Associate Professor
Allan FOUACHE profile picture FOUACHE Allan Ph.D Student
Laetitia GIBERT profile picture GIBERT Laetitia -
Linda IMIKIRENE profile picture IMIKIRENE Linda Intern
Jean-Marc LOBACCARO profile picture LOBACCARO Jean-Marc Professor
Salwan MAQDASY profile picture MAQDASY Salwan Assistant Clinician
Laurent MOREL profile picture MOREL Laurent Professor
Manuela PACCIARINI profile picture PACCIARINI Manuela Intern
Amandine RAMBUR profile picture RAMBUR Amandine Ph.D Student
Julie SALAGNAD profile picture SALAGNAD Julie Intern
Jean-Paul SARU profile picture SARU Jean-Paul Technical Assistant
Amalia TROUSSON profile picture TROUSSON Amalia Associate Professor

Publications