Yoan RENAUD
Bioinformatics research Ingeneer
Resume

Je suis Ingénieur de recherche en bioinformatique spécialisé dans le traitement et l'analyse de données biologiques.
Mes différentes missions dans le laboratioire sont les suivantes:
* Réalisation d'analyses de séquençages haut-débits (RNA-seq, ATAC-seq, ChIP-seq, 4C-seq, ....)
* Mise en place de nouvelles solutions et d'outils de traitement de données.
* Interaction avec les différentes équipes de recherche (differents modèles d'étude: humain, souris, drosophile, plante).
* Formation aux outils informatiques et bio informatiques (commandes bash, Serveur Galaxy, package R, ...., outils en ligne de commande)
* Mise en place d'une structure bioinformatique au sein du laboratoire (structuration de la demande des chercheurs, mise ne place de fiches de projets, mise en place de tickets electroniques pour les demandes, ...).
* Encadrement de stagiaires ( Master 1, Master 2 en bioinoformatique)
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Research
NonePublications
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2022
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“Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance.”, Advanced science (Weinheim, Baden-Wurttemberg, Germany), pp. e2200626, 2022.
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“L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus.”, Hum. Mol. Genet., 2022.
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2021
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“The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates Its Antiproliferative Activity in Mice.”, International journal of molecular sciences, vol. 23 (1) , 2021.
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“m(6)A RNA methylation regulates promoter- proximal pausing of RNA polymerase II.”, Molecular cell, 2021.
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“Gelsolin and dCryAB act downstream of muscle identity genes and contribute to preventing muscle splitting and branching in Drosophila.”, Scientific reports, vol. 11 (1) , pp. 13197, 2021.
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“Differential activation of JAK-STAT signaling reveals functional compartmentalization in Drosophila blood progenitors.”, eLife, vol. 10 , 2021.
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“Characterization of the Drosophila Adult Hematopoietic System Reveals a Rare Cell Population With Differentiation and Proliferation Potential.”, Frontiers in cell and developmental biology, vol. 9 , pp. 739357, 2021.
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“Transcriptomic and Genetic Analyses Identify the Kruppel-Like Factor Dar1 as a New Regulator of Tube-Shaped Long Tendon Development.”, Frontiers in cell and developmental biology, vol. 9 , pp. 747563, 2021.
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2020
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“Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.”, PLoS biology, vol. 18 (12) , pp. e3000948, 2020.
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“HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours.”, British journal of cancer, 2020.
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“Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila.”, Nature communications, vol. 11 (1) , pp. 2300, 2020.
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2019
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“Straightjacket/alpha2delta3 deregulation is associated with cardiac conduction defects in myotonic dystrophy type 1.”, eLife, vol. 8 , 2019.
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2018
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“Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1.”, Disease models & mechanisms, vol. 11 (5) , 2018.
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2015
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“Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance.”, Development, vol. 142 (5) , pp. 994–1005, 2015.
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“TRAP-rc, Translating Ribosome Affinity Purification from Rare Cell Populations of Drosophila Embryos.”, Journal of visualized experiments : JoVE, 2015.
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2014
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“Transcriptional properties and splicing of the flamenco piRNA cluster.”, EMBO Rep., vol. 15 (4) , pp. 411–8, 2014.
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2013
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“Novel Drosophila model of myotonic dystrophy type 1: phenotypic characterization and genome-wide view of altered gene expression.”, Hum. Mol. Genet., vol. 22 (14) , pp. 2795–810, 2013.
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2012
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“DroPNet: a web portal for integrated analysis of Drosophila protein-protein interaction networks.”, Nucleic Acids Res., vol. 40 (Web Server issue) , pp. W134–9, 2012.
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