Maria Eugenia GALLEGO

Professor, 1st Class.


Maria Eugenia GALLEGOprofile picture

Maria Gallego is professor of Genetics (PR1) at the University Blaise Pascal at Clermont-Ferrand, France and, with Charles White, co-directs a CNRS/INSERM/University research group studying the mechanisms by which cells maintain the integrity of their genomes. Her PhD at the University Autonoma of Madrid was followed by postdoctoral positions at the MRC London, Harvard Medical School Boston and Centre de Genetic Moleculaire, Gif-sur-Yvette France, working on the regulation of alternative mRNA splicing. In 1996 she started working on the molecular mechanisms of genetic recombination in plants at the University of Paris (Orsay) and moved to the University Blaise Pascal at Clermont-Ferrand in 1998 where she pursues research into the molecular mechanisms responsible for the maintenance of genome integrity in the model plant Arabidopsis thaliana. She has participated in four european network (EU Framework) grants as well as numerous public and industry funded projects in France.




  • 2019
    • T. Hirakawa, K. Kuwata, M. Gallego, C. White, M. Nomoto, Y. Tada and S. Matsunaga, “LSD1-LIKE1-mediated H3K4me2 demethylation is required for homologous recombination repair.”, Plant physiology, 2019.
  • 2018
  • 2017
  • 2016
  • 2015
    • M. Olivier, O. Da Ines, S. Amiard, H. Serra, C. Goubely, C. White and M. Gallego, “MUS81 and SEND1 are essential for telomere stability in Arabidopsis.”, Plant Cell, 2015.
    • V. Muchova, S. Amiard, I. Mozgova, M. Dvorackova, M. Gallego, C. White and J. Fajkus, “Homology-dependent repair is involved in 45S rDNA loss in plant CAF-1 mutants.”, Plant J., vol. 81 (2) , pp. 198–209, 2015.
    • P. Merle, M. Gueugneau, M. Teulade-Fichou, M. Muller-Barthelemy, S. Amiard, E. Chautard, C. Guetta, V. Dedieu, Y. Communal, J. Mergny, M. Gallego, C. White, P. Verrelle and A. Tchirkov, “Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.”, Scientific reports, vol. 5 , pp. 16255, 2015.
  • 2014
    • S. Amiard, M. Olivier, E. Allain, K. Choi, R. Smith-Unna, I. Henderson, C. White and M. Gallego, “Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.”, Nucleic Acids Res., vol. 42 (19) , pp. 11979–91, 2014.
    • O. Da Ines, M. Gallego and C. White, “Recombination-independent mechanisms and pairing of homologous chromosomes during meiosis in plants.”, Mol Plant, vol. 7 (3) , pp. 492–501, 2014.
    • I. Mestiri, F. Norre, M. Gallego and C. White, “Multiple host-cell recombination pathways act in Agrobacterium-mediated transformation of plant cells.”, Plant J., vol. 77 (4) , pp. 511–20, 2014.
    • S. Amiard, O. Da Ines, M. Gallego and C. White, “Responses to telomere erosion in plants.”, PLoS ONE, vol. 9 (1) , pp. e86220, 2014.
  • 2013
  • 2012
    • A. Ayar, S. Wehrkamp-Richter, J. Laffaire, S. Le Goff, J. Levy, S. Chaignon, H. Salmi, A. Lepicard, C. Sallaud, M. Gallego, C. White and W. Paul, “Gene targeting in maize by somatic ectopic recombination.”, Plant Biotechnol. J., vol. 11 (3) , pp. 305–14, 2012.
    • O. Da Ines, K. Abe, C. Goubely, M. Gallego and C. White, “Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana.”, PLoS Genet., vol. 8 (4) , pp. e1002636, 2012.
  • 2011
  • 2010
  • 2009
    • J. Vannier, A. Depeiges, C. White and M. Gallego, “ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana.”, PLoS Genet., vol. 5 (2) , pp. e1000380, 2009.
  • 2006
    • G. Maillet, C. White and M. Gallego, “Telomere-length regulation in inter-ecotype crosses of Arabidopsis.”, Plant molecular biology, vol. 62 (6) , pp. 859–66, 2006.
    • J. Vannier, A. Depeiges, C. White and M. Gallego, “Two roles for Rad50 in telomere maintenance.”, EMBO J., vol. 25 (19) , pp. 4577–85, 2006.
    • J. Bleuyard, M. Gallego and C. White, “Recent advances in understanding of the DNA double-strand break repair machinery of plants.”, DNA Repair (Amst.), vol. 5 (1) , pp. 1–12, 2006.
  • 2005
    • J. Bleuyard, M. Gallego, F. Savigny and C. White, “Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair.”, Plant J., vol. 41 (4) , pp. 533–45, 2005.
    • M. Gallego and C. White, “DNA repair and recombination functions in Arabidopsis telomere maintenance.”, Chromosome Res., vol. 13 (5) , pp. 481–91, 2005.
  • 2004
    • J. Bleuyard, M. Gallego and C. White, “Meiotic defects in the Arabidopsis rad50 mutant point to conservation of the MRX complex function in early stages of meiotic recombination.”, Chromosoma, vol. 113 (4) , pp. 197–203, 2004.
    • J. Bleuyard, M. Gallego and C. White, “The atspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation.”, Plant molecular biology, vol. 56 (2) , pp. 217–24, 2004.
    • S. Dubest, M. Gallego and C. White, “Roles of the AtErcc1 protein in recombination.”, Plant J., vol. 39 (3) , pp. 334–42, 2004.
  • 2003
    • M. Gallego, J. Bleuyard, S. Daoudal-Cotterell, N. Jallut and C. White, “Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis.”, Plant J., vol. 35 (5) , pp. 557–65, 2003.
  • 2002
    • S. Dubest, M. Gallego and C. White, “Role of the AtRad1p endonuclease in homologous recombination in plants.”, EMBO Rep., vol. 3 (11) , pp. 1049–54, 2002.
    • S. Daoudal-Cotterell, M. Gallego and C. White, “The plant Rad50-Mre11 protein complex.”, FEBS Lett., vol. 516 (1-3) , pp. 164–6, 2002.
  • 2001
    • H. Gherbi, M. Gallego, N. Jalut, J. Lucht, B. Hohn and C. White, “Homologous recombination in planta is stimulated in the absence of Rad50.”, EMBO Rep., vol. 2 (4) , pp. 287–91, 2001.
    • M. Gallego and C. White, “RAD50 function is essential for telomere maintenance in Arabidopsis.”, Proc. Natl. Acad. Sci. U.S.A., vol. 98 (4) , pp. 1711–6, 2001.
    • M. Gallego, M. Jeanneau, F. Granier, D. Bouchez, N. Bechtold and C. White, “Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity.”, Plant J., vol. 25 (1) , pp. 31–41, 2001.