Principal Investigator


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  • Principal Investigator, 2013
  • Chargée de Recherche, CNRS, Clermont-Ferrand, 2009-13, with Dr S. Tourmente
  • Postdoctoral Fellow, Curie Institute, Paris, 2005-09, with Dr G. Almouzni
  • PhD, Friedrich Miescher Institute, Basel, Switzerland, 2001-04, with Dr J. Paszkowski
  • Master in Biotechnology, ESBS, Strasbourg, 1997- 2000




  • 2018
    • M. Benoit, L. Simon, S. Desset, C. Duc, S. Cotterell, A. Poulet, S. Le Goff, C. Tatout and A. Probst, “Replication-coupled histone H3.1 deposition determines nucleosome composition and heterochromatin dynamics during Arabidopsis seedling development.”, The New phytologist, 2018.
    • G. Parry, A. Probst, C. Baroux and C. Tatout, “Meeting report - INDEPTH kick-off meeting.”, Journal of cell science, vol. 131 (12) , 2018.
    • L. Simon, F. Rabanal, T. Dubos, C. Oliver, D. Lauber, A. Poulet, A. Vogt, A. Mandlbauer, S. Le Goff, A. Sommer, H. Duborjal, C. Tatout and A. Probst, “Genetic and epigenetic variation in 5S ribosomal RNA genes reveals genome dynamics in Arabidopsis thaliana.”, Nucleic Acids Res., 2018.
    • A. Probst, “A Compendium of Methods to Analyze the Spatial Organization of Plant Chromatin.”, Meth. Mol. Biol., vol. 1675 , pp. 397–418, 2018.
    • L. Simon and A. Probst, “High-Affinity LNA-DNA Mixmer Probes for Detection of Chromosome-Specific Polymorphisms of 5S rDNA Repeats in Arabidopsis thaliana.”, Meth. Mol. Biol., vol. 1675 , pp. 481–491, 2018.
  • 2017
  • 2016
    • A. Poulet, A. Probst, K. Graumann, C. Tatout and D. Evans, “Exploring the evolution of the proteins of the plant nuclear envelope.”, Nucleus, pp. 0, 2016.
  • 2015
  • 2014
    • K. Graumann, E. Vanrobays, S. Tutois, A. Probst, D. Evans and C. Tatout, “Characterization of two distinct subfamilies of SUN-domain proteins in Arabidopsis and their interactions with the novel KASH-domain protein AtTIK.”, J. Exp. Bot., vol. 65 (22) , pp. 6499–512, 2014.
    • A. Poulet, I. Arganda-Carreras, D. Legland, A. Probst, P. Andrey and C. Tatout, “NucleusJ: an ImageJ plugin for quantifying 3D images of interphase nuclei.”, Bioinformatics (Oxford, England), 2014.
    • C. Tatout, D. Evans, E. Vanrobays, A. Probst and K. Graumann, “The plant LINC complex at the nuclear envelope.”, Chromosome Res., 2014.
    • M. Thomas, L. Pingault, A. Poulet, J. Duarte, M. Throude, S. Faure, J. Pichon, E. Paux, A. Probst and C. Tatout, “Evolutionary history of Methyltransferase 1 genes in hexaploid wheat.”, BMC genomics, vol. 15 , pp. 922, 2014.
  • 2013
    • M. Casanova, M. Pasternak, F. El Marjou, P. Le Baccon, A. Probst and G. Almouzni, “Heterochromatin reorganization during early mouse development requires a single-stranded noncoding transcript.”, Cell Rep, vol. 4 (6) , pp. 1156–67, 2013.
    • M. Benoit, E. Layat, S. Tourmente and A. Probst, “Heterochromatin dynamics during developmental transitions in Arabidopsis - a focus on ribosomal DNA loci.”, Gene, vol. 526 (1) , pp. 39–45, 2013.
  • 2012
    • E. Layat, A. Probst and S. Tourmente, “Structure, function and regulation of Transcription Factor IIIA: From Xenopus to Arabidopsis.”, Biochim. Biophys. Acta, vol. 1829 (3-4) , pp. 274–82, 2012.
  • 2011
    • G. Almouzni and A. Probst, “Heterochromatin maintenance and establishment: lessons from the mouse pericentromere.”, Nucleus, vol. 2 (5) , pp. 332–8, 2011.
    • A. Probst and G. Almouzni, “Heterochromatin establishment in the context of genome-wide epigenetic reprogramming.”, Trends Genet., vol. 27 (5) , pp. 177–85, 2011.
    • C. Maison, D. Bailly, D. Roche, R. Montes de Oca, A. Probst, I. Vassias, F. Dingli, B. Lombard, D. Loew, J. Quivy and G. Almouzni, “SUMOylation promotes de novo targeting of HP1alpha to pericentric heterochromatin.”, Nat. Genet., vol. 43 (3) , pp. 220–7, 2011.
    • C. Maison, J. Quivy, A. Probst and G. Almouzni, “Heterochromatin at mouse pericentromeres: a model for de novo heterochromatin formation and duplication during replication.”, Cold Spring Harb. Symp. Quant. Biol., vol. 75 , pp. 155–65, 2011.
  • 2010
    • A. Probst, I. Okamoto, M. Casanova, F. El Marjou, P. Le Baccon and G. Almouzni, “A strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development.”, Dev. Cell, vol. 19 (4) , pp. 625–38, 2010.
  • 2009
    • A. Probst, E. Dunleavy and G. Almouzni, “Epigenetic inheritance during the cell cycle.”, Nat. Rev. Mol. Cell Biol., vol. 10 (3) , pp. 192–206, 2009.
  • 2007
    • A. Probst and G. Almouzni, “Pericentric heterochromatin: dynamic organization during early development in mammals.”, Differentiation, vol. 76 (1) , pp. 15–23, 2007.
    • A. Probst, F. Santos, W. Reik, G. Almouzni and W. Dean, “Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote.”, Chromosoma, vol. 116 (4) , pp. 403–15, 2007.
  • 2006
    • Y. Habu, O. Mathieu, M. Tariq, A. Probst, C. Smathajitt, T. Zhu and J. Paszkowski, “Epigenetic regulation of transcription in intermediate heterochromatin.”, EMBO Rep., vol. 7 (12) , pp. 1279–84, 2006.
    • M. Houlard, S. Berlivet, A. Probst, J. Quivy, P. Hery, G. Almouzni and M. Gerard, “CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells.”, PLoS Genet., vol. 2 (11) , pp. e181, 2006.
    • N. Schonrock, V. Exner, A. Probst, W. Gruissem and L. Hennig, “Functional genomic analysis of CAF-1 mutants in Arabidopsis thaliana.”, J. biol. chem., vol. 281 (14) , pp. 9560–8, 2006.
  • 2005
    • O. Mathieu, A. Probst and J. Paszkowski, “Distinct regulation of histone H3 methylation at lysines 27 and 9 by CpG methylation in Arabidopsis.”, EMBO J., vol. 24 (15) , pp. 2783–91, 2005.
    • A. Pecinka, N. Kato, A. Meister, A. Probst, I. Schubert and E. Lam, “Tandem repetitive transgenes and fluorescent chromatin tags alter local interphase chromosome arrangement in Arabidopsis thaliana.”, Journal of cell science, vol. 118 (Pt 16) , pp. 3751–8, 2005.
  • 2004
    • C. Bowler, G. Benvenuto, P. Laflamme, D. Molino, A. Probst, M. Tariq and J. Paszkowski, “Chromatin techniques for plant cells.”, Plant J., vol. 39 (5) , pp. 776–89, 2004.
    • A. Probst, M. Fagard, F. Proux, P. Mourrain, S. Boutet, K. Earley, R. Lawrence, C. Pikaard, J. Murfett, I. Furner, H. Vaucheret and O. Mittelsten Scheid, “Arabidopsis histone deacetylase HDA6 is required for maintenance of transcriptional gene silencing and determines nuclear organization of rDNA repeats.”, Plant Cell, vol. 16 (4) , pp. 1021–34, 2004.
    • S. Takeda, Z. Tadele, I. Hofmann, A. Probst, K. Angelis, H. Kaya, T. Araki, T. Mengiste, O. Mittelsten Scheid, K. Shibahara, D. Scheel and J. Paszkowski, “BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in Arabidopsis.”, Genes Dev., vol. 18 (7) , pp. 782–93, 2004.
  • 2003
    • M. Tariq, H. Saze, A. Probst, J. Lichota, Y. Habu and J. Paszkowski, “Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin.”, Proc. Natl. Acad. Sci. U.S.A., vol. 100 (15) , pp. 8823–7, 2003.
    • A. Probst, P. Fransz, J. Paszkowski and O. Mittelsten Scheid, “Two means of transcriptional reactivation within heterochromatin.”, Plant J., vol. 33 (4) , pp. 743–9, 2003.
  • 2002
    • O. Mittelsten Scheid, A. Probst, K. Afsar and J. Paszkowski, “Two regulatory levels of transcriptional gene silencing in Arabidopsis.”, Proc. Natl. Acad. Sci. U.S.A., vol. 99 (21) , pp. 13659–62, 2002.